The C. Diff Studies will include about 150 patients with recurrent C. difficile (C. Diff) infections and will be conducted at various study sites throughout the USA. All study-related care will be provided by specialty physicians and a dedicated study team.

If you qualify for a study, you will visit a study clinic in your area approximately 5 times over 24 weeks.  

The C. Diff Studies will be evaluating the efficacy of an investigational study drug for C. difficile (C. Diff). Volunteers who qualify to take part in a study may receive compensation for time and travel expenses.

  • 1
    If you are 18 years of age or older and have experienced one or more C. difficile infections.
  • 2
    All study-related care is provided at no cost. You do not need health insurance to participate.
  • 3
    Volunteers who take part in a study may be eligible to receive compensation for their time and travel.
  • 4
    Participants will receive all study-related care from a team of medical professionals at no cost. The studies will require routine visits to a research center in your area.

Who can take part in the C. Diff Studies?

You may be eligible to take part in the C. Diff Studies if you:

  • 1
    Are at least 18 years of age and.
  • 2
    Have experienced 2 or more episodes of C. difficile (C. Diff) within the last 6 months.
  •  
    OR
  • 3
    Are at least 65 years of age and.
  • 4
    Are experiencing an episode of C. difficile (C. Diff) which started in the past 30 days.

All study-related care will be provided by a team of medical professionals.

Volunteers who take part in a study may be eligible to receive compensation for their time and travel.
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About C. Difficile Infections (C. diff)

C. Difficile bacteria exists all around us, in the water we drink, the air we breathe, and in the soil that grows our food. Humans along with other animals have C. Diff bacteria in their intestines, and never have symptoms of an infection.

When people are given antibiotics to fight off infections, this can trigger various different infections such as C. Diff. Because the body contains thousands of different types of bacteria (some good, along with some bad), antibiotics may kill enough of the good, healthy ones that bad and unhealthy bacteria can take over.

C. Diff can spread in places like hospitals, long-term care homes, and healthcare facilities, where workers are likely to come into contact with the bacteria and spread it to others. It is also contractible through touching surfaces like sheets or clothing, that then touch your mouth, eyes or nose.

Typically, older adults are at a greater risk of contracting a C. Diff infection, especially when taking antibiotics, although young people may also develop C. Diff due to hospital stays, antibiotic use, or failure to properly washing their hands.

The most indicative symptoms of C. Diff are visiting the washroom several times a day and passing watery stool accompanied by a very strong odor and abdominal cramping.

Other symptoms can include:

  • Watery diarrhea two or more times a day
  • Abdominal cramping and tenderness
  • Fever
  • Nausea
  • Swollen abdomen
  • Loss of appetite
  • Dehydration
  • strong, distinct odor

The C. Diff Studies are evaluating the efficacy of an investigational study drug for C. difficile (C. Diff). Volunteers who qualify to take part in a study may receive compensation for time and travel expenses.

Frequently Asked Questions

Your participation in a study will last about 24 weeks. The study will include 5 visits to a study clinic in your area and follow up phone calls at designated times.

At visits, you will undergo general physical examination procedures to assess your wellbeing (e.g. height, weight, blood pressure).

All study-related care is provided at no cost to you. You do not need health insurance to participate.

Volunteers who take part in the study may receive compensation for their time and travel.

Participation is entirely voluntary. Even if you decide to take part in this study, you can change your mind about participating at any time.

What is a Clinical Research Study?

A Clinical research study (also called a clinical trial) is a medical study that helps to answer important questions about an investigational drug or device, such as: Does it work, or how effective is it compared to another drug/device?

All medications must be tested in clinical research studies before they can be approved by regulatory authorities for doctors to prescribe to patients. Without people taking part in these studies, we would have no new treatments. The volunteers who participate in clinical research studies play a major role in helping to advance medicine.

There is no cost to participate in the C. Diff Studies. If you qualify, the investigational drug, study-related tests, assessments, and visits will be provided to you at no cost. You will receive study-related care throughout the study from a team of professional doctors and nurses.

Volunteers who take part in the studies may be compensated for their time and travel. Please discuss this with the study team when they contact you.

Sign Up

What happens if I Sign Up? If you sign up, we will match you to a study clinic in your area that is seeking participants or notify you if one becomes available. They will contact you to explain more about the study before you make your decision about participating. You will attend an in-person visit where the study team will help determine if you qualify and if the study is right for you.


If you think you might like to participate in the C. Diff Studies or would like more information, please enter your information below so we can see if you may qualify and can contact you about the studies. Keep in mind that participation is entirely voluntary. If you do decide to take part in a study, you may change your mind about participating at any time.